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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28aff0f0258b3d0b7f39c67b445004039e07d2fde8e7172ff3750b905d1be5fd' 
  AND token = 'YaMxwq+jDcC5DjTuDiPtERwKBJ3QowF5PJLJKMOOdnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}