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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a10fb535697fbb32b086866df4e521bb068539912cd3d124d4eec7cfa92b018' 
  AND token = 'UsyF3x71ItbAvSbizQ5VpVOW75zCdgCZYHCAqjR3xfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}