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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a14b307435adf4e69c1e1ad65bfa42f2dc833b64e521e87b187351d23ebfe3a' 
  AND token = 'jWLPzJ+8maTu4I+OZiRHyIDby7pgKv1uo3+zOO+FifM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}