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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17ae194a1be6940eb101e20a28bc23eae69cfefb6951228fc740a30813d19aed' 
  AND token = '9hOJB/cCBeu3aqq+yKTtXy6Uhb8WBC0rI5g5Glz5Rds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}