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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66736948e27e5587f74a8368b4fd82fc9b93bd30b5a1553813759074a876d19' 
  AND token = 'kCjpCeV7Y4T5uXctswPIkJuOMHswQp9kLgfDAkrf5dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}