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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6278cb4450d6ce84b337c9c84be4d125664b9a30c5c491b891dbfe8308a5a04c' 
  AND token = 'oImItEY7KVIeUliHpsc7n3EOCgbfMFHRWvxVGx1jsCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}