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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b7e35ab7d214528e3f74484a13bc0414a06e04ea6162fa3a32264df3e06e166' 
  AND token = 'pGE7ZWzvbJyb0o1cST8bVSJzuI0IM9CD+bZd/icVpL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}