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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00df03b4944ee892fe02d1589ff5fc25d7f714df05dc1b8375fac62b4c4de923' 
  AND token = '+S4k8UwAAGSbh5R30fOpw/vptqTAkBZNfIA8W+XYqk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}