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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a244093fb8082803d1d04038a542d169b2f3af44cf6b57560e3652125cf8ca7' 
  AND token = 'E/jqGh+PAW6Ixm+vdAXCcIf6nMoScLrs/CAXe/DtuKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}