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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b256bda6b66312a3f2eaf3171a8ce714a18823275281fee78cc6dd88ac4ada94' 
  AND token = 'bz0f/UE28PD1IvOIE2GcQCVMX+dR3Ky/XQESfygcNB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}