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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d2a894364fdecf202b755cbad07ba822fcf5749d204732403a6fa29857f4f91' 
  AND token = 'ToX6xNE2USeKFKiT77ewyZZtMy+idi9rU3YJ1tGzIGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}