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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f59f83e00b0efefa2575c4288f053dd3ed0bd5e1d91485e0c245897ecc376b5d' 
  AND token = 'r4yiJM+5b5x+9ru9R/3R8RbiTPtzoMnW15js73MwRyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}