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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41a994a2c96b91c2a5bc646d9e6649472c700ceb56b980c74a4b91afbad085b9' 
  AND token = 'FisEchDK8nKy6O2QXLaJUq+hkjN3LisS+IQz2lwMTUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}