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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '627d24b785740519b6aeb16aa3b0888494b5daf8851bea31b7db14eab6c76408' 
  AND token = 'aqK7LohplYsaCt+e4u53k+JIhAA3MRQQpPkgdgcWqzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}