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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c4cba88362e8cc91e980fdde60c8bac863fc9288f5d97ce4e7af72dff41553' 
  AND token = 'fJ9drPCx47wqt4lOFSxWsxuIlBWYleg+5JPQsxdV/E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}