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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2f225e3e361fdac1a998e6915be26e93a4f8ec4a18aaccd9bc39c9bb64d71a' 
  AND token = '49F4Oc/IXc6duOEzn3f04GF0GKRSgi0kuXIZJ529ZeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}