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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d2927f261906d3e0c6cf149ed51f9ee925780e8d7b86b64f5eacb3e2c1c8534' 
  AND token = 'u74/Xn6afq/48/+jEADWruz4Afqkl0kQe5EBdz0kjMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}