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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74a7c39a457affe27ea53486c4adda0c3d01c498341b281e9c296cf8bfcb8ca7' 
  AND token = 'eSQ1kgGP6WEbO0U+7tKcEchXRd7YsVsfQgtKPP1g3bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}