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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c926fad789173936e94fb7a3712cb882f80a2964f41aec2c075ba6f172d4891f' 
  AND token = 'Yjka4f1I2Skr+24zM44eMbyz7mSf/Pz737c/Hp+0jS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}