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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ab86281f7bfa1a0655f2a7478c0572d86e6b00e7dc550b26129a9a25f13cfa2' 
  AND token = 'HXlnv0S0p+gztpWFLsAolC0cLEpEsBdvcEKHK4m90eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}