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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a643d445166031bea37a9eb6c0f527a8865bf1e63d5ed96d0a6c96d7b2505dc8' 
  AND token = 'EKHCCVDRf2V6YPu4g/LwDxjCbR3dQNDWue2Urpl7Lyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}