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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8395b1d176daf1ddb0db75bc42be4ed8b70d1880dd527e59f3c63a2329f44f51' 
  AND token = 'y+tmVM6JOYugdlJfunaX5oi5daZt1hds0Ig2jLxTXqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}