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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2043dff04bc6dec4991f974c5585822883d479d9177f66405abee700acf302fb' 
  AND token = 'P6R2d9BAGuuGKha3iJxv+iv+dXfvduuuI6NA2qteEbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}