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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8992e88a0126fe1e3ecb9089aa970f1623f64a0d598381536ea07349c889c5e7' 
  AND token = 'nvexHrAnU8o2JfTWLj1C8+tRgIoU3IXF8YvcJ71cf5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}