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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a724eb32e8021f02eb27849adfc129306b847c1a9aff7c1b2bed227c9e198b8' 
  AND token = 'HICPO47TwV0dmgYNlFITMb/PTFVOccXhxMSywkvYtzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}