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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42852586fe4d041e9cb9ebf2bb4157d27e1ba18275f8c003d9791be210cb7015' 
  AND token = 'zVSsZpWGiBmKT5BT4M9+2w9qEknE1qHZwx1JZSCqEUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}