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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe35f446ac6bd5e773671f160e7d6446a011144d93cafb9d2c8063349e8fe9a7' 
  AND token = '4ad5CGN2KyoXn1yWTC0hODUU859KMprk6opWFxEYlAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}