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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b28bbc42082d79e26a310f592b189b09a9718c7c1881876031a2781caa007d1' 
  AND token = 'DxabOGhQrT1aJU+uFeeoKCc55cEuX8JrJqvfqMTwehk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}