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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b81c450beeb9a7c78f63ce9a682c4ee16c65e1db62bbcfb96344c1721b85550' 
  AND token = 'Dz1+0/OK8MhyPFl2pw7eIWKqoaEqQ0ZIPr+RhWp2OaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}