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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '597ff80df56a48d0b52c71dda1ee4faf3390dc0a83715c39c7ac6444c2fc2291' 
  AND token = 't0FYST4ll38pKuqdxbKOIlMA1EvYhjuAxE698Zq2mtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}