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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b5ec985d3cc938dc5d625c40b0a002c27d8f50b23d2bff9d87c0456298f41b4' 
  AND token = 'igm2MIThLmT1eh77Uog5kwbjUUQuyEqKJLrGNTSdf58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}