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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ad268d86644f91bc988934bb1a860d6c46245bd11ff0c1aee58fef214dc3f4' 
  AND token = '8I6Pwpgi96FRzhAFSX7Bl1FEWQ4DjnDH6MIstRbH7Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}