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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535a422448d4a70d55c48a60efa55c595b95283c4f24b10513cc8a9a37a8b071' 
  AND token = 'zXSB0fwDCkhhtdnPpuqfuw5BDRzZ1cpBb7G38woDF7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}