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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aecccc91f1b6d60c5b024e7125a5e1fba41bf5477dff0450c33b7fb8edb39e4b' 
  AND token = 'KlUgL1IJgTvQ9z+YAoS118CWq3Ecbvrj1TopcZx5PWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}