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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65df43183f837b8a6bfa59e605fc83feb7474141e1435c5e4b867fb3ea57886b' 
  AND token = 'xAAckDog3gIwOmfVdQAsec6ggAicLlldk+AJQT4xiws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}