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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9ae7249fd1f890b86b72e2da4d71ca740610592731317375a051919abd4fd93' 
  AND token = '9LjB1YAuW9naOHqQyTyPVP3ih+arSTgwXCRs2+KuBe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}