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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4acaa024a6cd19de0558112a755a5422dacca2c4921200523d3570fe99877262' 
  AND token = 'VpVsx035vTwxx5e0a9sJQRWOza3uDs+aZAjbF4CFAV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}