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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc875ce3d291b7764f3ede04164bd2c5b05c23f915a2cd3b78700c6afee03901' 
  AND token = 'GLFSHIfKw6HGSzTaLMeBY1s9WH4zCZ6kBbq9uDlB3vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}