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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7b6e851a602e461e3a7b586460b72733a21a897fc8def17d4f0c27cdb1f03a9' 
  AND token = 'L5B4xWdv6upSWCyhCXphA7ZMBfToJ/kEUp9Ibvl9i9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}