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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b293f99b57e8a01dfcebf623394f9960623d2f1e521d344e841ec3e332c1f84' 
  AND token = 'JO5waNshyVB/WQ702PGB9MaBMlXnJovTdakKtIucgZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}