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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '394b8325445aaabfd7f57a9ce674095962f35a50bb00e59f80a7bf54b3ab073e' 
  AND token = 'Gk8PYpAYgHt+jqNUobajFa9WbrvPeN3dviReG76QyRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}