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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e00816d5b2d22611bed12f189a1a41a109449762ef6a149912f20a1892181d62' 
  AND token = '3pF3yEqTCRIPafDcRyK6/ND+Ha6YRl6F7P9Z+vi9xNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}