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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a95fa4364082d13978f5b00d81793cad7f68f5a92bee61db1f1d2e379092678' 
  AND token = 'NDZLUr9+mAhuBfZWvSY6aumxRX+x5RaXiXCXyzWCUIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}