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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8357cb37f9d541ab73cbd43f3debb03c40bad2f327de243d0a633714715340c4' 
  AND token = '+ew9mB+NJ+AnEEyS3aUHGxvQ72sqvGaFRd3YHzjNZos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}