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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fd74d6bf47697c13664b08682f55105b612464d9e16baeade3f4baad8ee9da1' 
  AND token = '+uuEe82TWvoGOswSJQyUdoCibvo4T/YVIN7JtHWE7ZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}