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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4c355b6a026dfb23bc80c4b9e78a2f4977cba81fccac8417372051469f9cf3' 
  AND token = 'zc6GrmF4TJ6PxmPcZuo7E0Qgj2PimPbkWjINiyGVmI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}