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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5d2e431bea42170cfd718d40f82610d2a18ddfc79707a4500f88301faabdddc' 
  AND token = 'ez75ATIbWs6nTmLATc+FjAXJWCL3l506xwII5VJyMrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}