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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd28aa8c307d50a1bed68cffa7153aaf6b6cc27e7fa6ea3fd8e2046dd1907d9ed' 
  AND token = 'DIc5cYAM9tAub1zAwBpp6J+RSmgV8XBZDCkmIyTSCiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}