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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11d00b9eeb9952acd7e161bf2b34491c04c3342b1641e9deee8b3325a7bc562a' 
  AND token = 'k6UpkFiinbVhJmHz3EHAzhIlPIZTOgrDJ3V0/d583Kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}