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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edbd8fbd681556ebcbbe2da6e18c174881c9685fd9ef5042143a10327d4c8c70' 
  AND token = '9pRJ5SGMAbwoGFEdkMpKm/v2gyzNT8+Pyzu0yT7wj8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}